2013

Journal Publications top

Ding, X., Xu, H., Hopper, C., Yang, J., and Ho, C.M., “Use of fractional factorial designs in antiviral drug studies“, Quality and Reliability Engineering International, Vol. 29, Issue 2, pp. 299-304, 2013.

Jaynes, J., Ding X., Xu, H., Wong, W.K., and C.M. Ho, “Application of Fractional Factorial Designs to Study Drug Combinations“, Statistics in Medicine, Vol. 32, Issue 2, pp. 307-318, 2013.

Wang, H., Silva, A., and Ho, C.M., “When Medicine Meets Engineering – Paradigm Shifts in Diagnostics and Therapeutics”, Diagnostics, Vol. 3, pp. 126-154, 2013.

Lillehoj, P.B., Kaplan, C. W., He, J., Shi, W., and Ho, C .M.,”Rapid, Electrical Impedance Detection of Bacterial Pathogens Using Immobilized Antimicrobial Peptides“, Journal of Laboratory Automation, DOI: 10.1177/2211068213495207, 2013

Takeuchi, M., Haulot, G. and Ho, C.M., “System Integration of a Novel Cell Interrogation Platform“, IN: Micro-Nano Mechatronics – New Trends in Material, Measurement, Control, Manufacturing and Their Applications in Biomedical Engineering, ed. Fukuda, T., Niimi, T. and Obinata, G., pub. InTech, pp. 299-314 (2013).

2012

Journal Publications top

Chen T.-H., Zhu X., Pan L., Zeng X., Garfinkel A., Tintut Y., Demer L. L., Zhao X., Ho C.M., “Directing Tissue Morphogenesis via Self-Assembly of Vascular Mesenchymal Cells“,  Biomaterials, vol. 33, pp. 2019-2026, 2012.

Chen T.-H., Guo C., Zhao X., Wong M. N., Tintut Y., Demer L. L., Ho C.M., Garfinkel A., “Patterns of periodic holes created by increased cell motility“, Interface Focus, vol. 2, pp. 457-64, 2012.

Chen T.-H., Hsu J. J., Zhao X., Guo C., Wong M. N., Huang Y., Li Z., Garfinkel A., Ho C.M., Tintut Y., Demer L. L., “Left-Right Symmetry Breaking in Tissue Morphogenesis via Cytoskeletal Mechanics“, Circulation Research, vol. 110, pp. 551–559, 2012.

Ding, X.T, Xu, H.Q, Hopper C., Yang J., and Ho C.M., “Use of Fractional Factorial Designs in Antiviral Drug Studies”, Quality and Reliability Engineering International, DOI: 10.1002/qre.1308, 2012.

Ding, X. T., Sanchez, D. J., Shahangian, A., Al-Shyoukh, I., Cheng, G., and Ho, C. M., “Cascade Search for HSV-1 Combinatorial Drugs with High Antiviral Efficacy and Low Toxicity”, International Journal of Nanomedicine, Vol. 7, 2281-2292, 2012.

Jaynes, J., Ding, X.T., Xu, H., Wong, W.K., and Ho, C.M., “Application of Fractional Factorial Designs to Study Drug Combinations”, Statistics in Medicine, DOI, 10.1002/sim.5526, 2012.

Wong, I, Ding, X., Wu, C. and Ho, C.M., “Accurate and effective live bacteria microarray patterning on thick polycationic polymer layers co-patterned with HMDS”, RSC Advances, 2 (20), 7673 – 7676, DOI: 10.1039/c2ra20938a, 2012

Wei F., Cheng, S., Korin, Y., Reed,E.F., Gjertson, D., Ho,C. M., Gritsch, H.A., and Veale, J., “Serum Creatinine Detection by a Conducting-Polymer-Based Electrochemical Sensor To Identify Allograft Dysfunction”, Analytical Chemistry, 2012.

Haulot, G., Benahmed, A. J. and Ho, C. M., “Optoelectronic Reconfigurable Microchannels”, Lab Chip, 12 (23), pp. 5086 – 5092, 2012

2011

Journal Publications top

Wong T.-S., Chen T.-H.,  Shen X., and Ho C.M., “Nanochromatography Driven by the coffee Ring Effect,“ Analytical Chemistry, vol. 83, pp. 1871–1873, 2011.

Valamehr, B., Tsutsui, H., Ho, C.M., and Wu, H., “Developing Defined Culture Systems for Human Pluripotent Stem Cells,” Regenerative Medicine, Vol. 6, pp. 623-634, 2011.

Tsutsui, H., Valamehr, B., Hindoyan, A., Qiao, R., Ding, X., Guo, S., Witte, O.N., Liu, X., Ho, C.M., and Wu, H., “An Optimized Small Molecule Inhibitor Cocktail Supports Long-term Maintenance of Human Embryonic Stem Cells,” Nature Communications, 2:167, DOI:10.1038/ncomms1165, 2011.

Wu, Chunsheng, Lillehoj, P.B., Sabet, L., Wang, P. and Ho, C.M., “Ultrasonication on a microfluidic chip to lyse single and multiple Pseudo-nitzschia for marine biotoxin analysis“, Biotechnology Journal, 5(2): 150-155, 2011.

Al-Shyoukh, I., Yu, F., Feng, J., Yan, K., Dubinett, S., Ho, C. M., Shamma, J.S. and Sun R., “Systematic quantitative characterization of cellular responses induced by multiple signals“, BMC Systems Biology, Vol. 5, pp. 88, 2011.

Yu, F., Al-Shyoukh, I., Feng, J., Li, X., Liao, C.W., Ho, C.M., Shamma, J.S., Sun R., “Control of Kaposi’s Sarcoma-Associated Herpesvirus Reactivation Induced by Multiple Signals”, Plos ONE, Vol. 6, Issue 6, pp. 1-13, 2011.

Lee, J., Newbern, S., Tai, Y.C., Ho, C.M., and Huang, P.H., “Flight demonstrations of micro-actuator controlled delta wing”, Aircraft Engineering and Aerospace Technology, Vol. 83, Issue 5, pp. 324-331, 2011.

Haulot. G. and Ho, C.M.,“Optoelectronic Heating for Fabricating Microfluidic Circuitry”, Advances in OptoElectronics, Volume 2011, Article ID 237026, doi:10.1155/2011/237026, 2011.

Wei, F., Bai, B., and Ho, C. M., “Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme”, Biosensors and Bioelectronics, Vol. 30, pp. 174-179, 2011.

2010

Journal Publications top

Tsutsui, H., Yu, E., Marquina, S., Valamehr, B., Wong, I., Wu, H., and Ho, C.M., “Efficient Dielectrophoretic Patterning of Embryonic Stem Cells in Energy Landscapes Defined by Hydrogel Geometries,” Annals of Biomedical Engineering, Vol. 38, pp. 3777-3788, 2010.

Lillehoj, P.B., Tsutsui, H., Valamehr, B., Wu, H. and Ho, C.M., “Continuous sorting of heterogeneous-sized embryoid bodies“, Lab Chip, 10, 1678 – 1682, 2010.

L. Li, M. B. Finnegan, S. Özkan, Y. Kim, P.B. Lillehoj, C.-M. Ho, R. Lux, R. Mito, Z. Loewy, and W. Shi, “In Vitro Study of Biofilm Formation and Effectiveness of Antimicrobial Treatment on Various Dental Material Surfaces“, Molecular Oral Microbiology, 25, 382-390, 2010.

Ho, D. and Ho, C.M., “System Control-Mediated Drug Delivery Towards Complex Systems via Nanodiamond Carriers“, International Journal of Smart and Nano Materials, v. 1. no.1 p,70-81, 2010.

Lillehoj, P.B., Wei, F. and Ho, C. M., “A self-pumping lab-on-a-chip for rapid detection of botulinum toxin“, Lab Chip, 10, 2265 – 2270, 2010.

Garcia, D., Chen T.H., Wei, F. and Ho, C.M., “A Parametric Design Study of an Electrochemical Sensor“, JALA, 2010.

Wei, F., Lillehoj, P. and Ho, C.M., “DNA Diagnostics: Nanotechnology-enhanced Electrochemical Detection of Nucleic Acids“, Pediatr Res, 67(5):458-468, 2010. PMCID: PMC2876983

Wong, I., Atsumi, S., Huang, W.C., Wu, T.Y., Hanai, T., Lam, M.L., Tang, P., Yang, J., Liao, J.C., and Ho, C.M., “An agar gel membrane-PDMS hybrid microfluidic device for long term single cell dynamic study”, Lab Chip 20, pp. 2710-2719, 2010.

Shen, X.Y., Ho, C.M., and Wong, T.S., “Minimal Size of Coffee Ring Structure”, J. Phys. Chem B, Vol. 114, No. 7, pp. 5269-5274, 2010.

Ho, C.M., Wong, T.S., and Shen, X.Y, “Coffee rings for Microscale Biomolecular Processing”, SPIE Newsroom, DOI: 10.1117/2.1201006.003067, 2010.

2009

Journal Publications top

Wong, T.-S. and Ho, C.-M., “Dependence of Macroscopic Wetting on Nanoscopic Surface Textures”, Langmuir, vol. 25, pp. 12851 – 12854, 2009.

Gu, F., Li, Y., Zhou, C., Wong, D.T.W., Ho, C.-M., Qi, F., and Shi, W., “Bacterial 16S rRNA/rDNA Profiling in the Liquid Phase of Human Saliva”, The Open Dentistry Journal, vol. 3, pp. 80 – 84, 2009.

Wei, F., Liao, W., Zhang, L., Arellano-Garcia, M., Hu, Shen, Wong, D.T., and Ho, C.M., “Electrochemical Sensor for Oral Cancer Detection with Multiplex Salivary Biomarkers”, Clinical Cancer Research, vol. 15, pp. OF1 – OF7, 2009.

Wong, T.-S., Huang, A.P.-H., and Ho, C.-M., “Wetting Behaviors of Individual Nanostructures”, Langmuir, vol. 25, 6599 – 6603, 2009.

Wong, I. and Ho, C.-M., “Surface Molecular Property Modifications for Poly(dimethylsiloxane) (PDMS) Based Microfluidic Devices”, Microfluidics and Nanofluidics, vol. 7, pp. 291 – 306, 2009.

Wei, F., Liao, W., Xu, Z., Yang, Y., Wong, D.T., Ho, C.-M., “A Bio-abiotic Interface Constructed by Nanoscale DNA-Dendrimer and Conducting Polymer for Ultra-sensitive Bio-molecular Diagnosis”, Small, vol. 5, pp. 1784 – 1790, 2009.

Wei, F. and Ho, C.-M., “Aptamer-based Electrochemical Biosensor for Botulinum Neurotoxin”, Analytical and Bioanalytical Chemistry, vol. 393, pp. 1943 – 1948, 2009.

Wong, T.-S., Brough, B., and Ho, C.-M., “Creation of Functional Micro/Nano Systems through Top-down and Bottom-up Approaches”, Molecular and Cellular Biomechanics, vol. 6, pp. 1 – 56, 2009.

Tsutsui, H. and Ho, C.M., “Cell Separation by Non-Inertial Force Fields in Microfluidic Systems”, Mechanics Research Communication, vol. 36, pp. 92 – 103, 2009.

Sun, C.P., Usui, T., Yu, F., Al-Shyoukh, I., Shamma, J., Sun, R., and Ho, C.M., “Integrative Systems Control Approach for Reactivating Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) with Combinatory Drugs”, Integrative Biology, vol. 1, pp. 123 – 130, 2009.

Yue, Z.C., Zhang, F.F., Liu, Y.H. and Ho, C.M., “Interrogating a cell signalling network sensitively monitors cell fate transition during early differentiation of mouse embryonic stem cells”, Science China-Life Science, V. 53, pp. 78-86, doi: 10.1007/s11427-010-0010-y, 2009.

Wong, I, and Ho, C. M., “Surface molecular property modifications for poly (dimethylsiloxane) (PDMS) based microfluidic devices”, Microfluidics and Nanofluidics: Vol. 7, Issue 3, pp. 291-306, 2009.

2008

Journal Publications top

Ulmanella, U. and Ho, C.M., “Molecular Effects on Boundary Condition in Micro/Nanoliquid Flows”, Phys. Fluids, vol. 20, 101512, 2008.

Li, N. and Ho, C.M., “Patterning Functional Proteins with High Selectivity for Biosensor Applications”, Journal of the Association for Laboratory Automation, vol. 13, pp. 237 – 242, 2008

Li, N. and Ho, C.M., “Photolithographic Patterning of Organosilane Monolayer for Generating Large Area Two-Dimensional B Lymphocyte Arrays”, Lab on a Chip, vol. 8, pp. 2105 – 2112, 2008.

Ma, Y., Sun, C.P., Fields, M., Li, Y., Haake, D.A., Churchill, B.M., and Ho, C.M., “An Unsteady Microfluidic T-form Mixer Perturbed by Hydrodynamic Pressure”, J. Micromech. Microeng., vol. 18, 045015, 2008.

Sabet, L., Tan, W., Wei, F., and Ho, C.M., “Reading Cancer-Specific Signatures”, SPIE Newsroom, DOI: 10.1117/2.1200809.1327.

Wong, P.K., Yu, F., Shahangian, A., Cheng, G., Sun, R. and Ho, C.-M., “Closed-loop Control of Cellular Functions Using Combinatory Drugs Guided by a Stochastic Search Algorithm”, Proceedings of National Academy of Sciences, Vol. 105, pp. 5105 – 5110, 2008.

Tan, W., Sabet, L., Li, Y., Yu, T., Klokkevold, P.R., Wong, D.T., and Ho, C.-M., “Optical Protein Sensor for Detecting Cancer Markers in Saliva”, Biosensors and Bioelectronics, Vol. 24, pp. 266 – 271, 2008.

Wei, F., Wang J., Liao, W., Zimmermann, B.G., Wong, D.T. and Ho, C.-M., “Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe”, Nucleic Acids Research, Vol. 36, e65, 2008.

Li, Na and Ho, C.-M., “Aptamer-Based Optical Probes with Separated Molecular Recognition and Signal Transduction Modules”, Journal of the American Chemical Society, Vol. 130, 2380-2381, 2008.

2007

Journal Publications top

Ho, C.-M. and Chen, J.M., “The Convergence of Bio, Nano and Information Technologies”, IEEE Nanotechnology Magazine, vol. 1, No. 1, pp. 18 – 21, 2007

Lee, Y.-K., Shih, C., Tabeling, P. and Ho, C.-M., “Experimental study and nonlinear dynamic analysis of time-periodic micro chaotic mixers”, Journal of Fluid Mechanics, Vol. 575, 425-448, 2007.

Lin, Y., Wong, T.S., Bhardwaj, U., Chen, J.M., Ho, C.M. and McCabe, E., “Formation of High Electromagnetic Gradient through Particle-based Microfluidic Approach”, Journal of Micromechanics and Microengineering, Vol. 17, pp. 1299 – 1306, 2007.

Brough, B., Christman, K.L., Wong, T.S., Kolodziej, C.M., Forbes, J.G., Wang, K., Maynard, H.D. and Ho, C.M., “Surface Initiated Actin Polymerization from Top-down Manufactured Nanopatterns”, Soft Matter, Vol. 3, pp. 541 – 546, 2007.

Benahmed, A., Lam, R., Rechner, N. and Ho, C.M., “Period and Height Control during the Microcontact Printing of Alkoxysilane for Optical Grating,” Journal of Microlithography, Microfabrication, and Microsystems 06(02), April 1, 2007.

Benahmed, A. and Ho, C.M., “Bandgap-Assisted Surface-Plasmon Sensing”, Applied Optics, Vol. 46, Issue 16, pp. 3369 – 3375, 2007.

Wong, T.S., Kumar, A.S. and Ho, C.M., “Surface Forces Modified by Engineered Micro/Nanostructures”, IEEE Review on Advances in Micro, Nano, Molecular Systems, Vol. 1, pp. 1 – 13, 2007.

2006

Journal Publications top

Cubaud, T., Ulmanella, U., and Ho, C.M., “Two-Phase Flow in Microchannels with Surface Modifications,” Fluid Dynamics Research, Vol. 38, Issue 11, November 2006, Pages 772-786, November 2006.

Brough B., Northrop B., Schmidt J., Tseng, H., Houk K., Stoddart  F., Ho, C. M., “Evaluation of Synthetic Linear Motor-Molecule Actuation Energetics”, Proceedings of National Academy of Sciences, vol. 103, pp.8583–8588, 2006.

Ho, D., Garcia, D. and Ho, C.M., “Nanomanufacturing and Characterization Modalities for Bio-Nano-Informatics Systems”, Journal of Nanoscience and Nanotechnology, Vol. 6, 875-891, 2006.

Huang, P.H., Wong, T.S. and Ho, C.M., “Silicone Polymer Chemical Vapor Sensors Fabricated by Direct Polymer Patterning on Substrate Technique (DDPOST)”, Sensors and Actuators B, Chemical, Vol. 116, pp. 2 – 10, 2006.

Choi, C.H., Ulmanella, U., Kim, J., Ho, C.M., and Kim, C.J., “Effective Slip and Friction Reduction in Nanograted Superhydrophobic Microchannels,” Physics of Fluids 18(8), 2006.

Chen, J. M. and Ho, C.-M., “Path to Bio-Nano-Information Fusion” IN: Progess in Convergence Technologies for Human Beings, Annals of the New York Academy of Sciences, Bainbridge, W.S. and Roco, M.C. (Ed.), Blackwell Publishing, Vol. 1093, pp. 123-142 (2006).

Xu, B., Lee, Y.K., Jin, Q., Zhao, J., and Ho, C.M., “ Multilayer SU-8 based microdispenser for microarray assay”, Sensors and Actuators A 132, pp. 714-725, 2006.

Huang, T.J., Flood, A.H., Brough, B., Liu, Y., Bonvallet, P.A., Kang, S., Chu , C.W., Guo, T.F., Lu, W., Yang, Y., Stoddart, J.F. and Ho, C.M., “Understanding and Harnessing Biomimetic Molecular Machines for NEMS Actuation Materials”, IEEE Transactions on Automation Science and Engineering, , 2006.

2005

Journal Publications top

Cubaud, T., Tatineni, M., Zhong, X, and Ho, C.M., “Bubble Dispenser in Microfluidic Devices,” Physical Review E, 72, 037302, 2005.

Pak Kin Wong, Winny Tan and Chih-Ming Ho “Cell Relaxation after Electrodeformation: Effect of latrunculin A on actin cytoskeleton“, Journal of Biomechanics Vol 38, 529-535, 2005.

Yang, C.Y., Brooks, E., Li, Y., Denny, P., Ho, C.M., Qi, F., Shi, W., Wolinsky, L., Wu, B., Wong, D. and Montamagno, C, “Detection of Picomolar Levels of Interleukin-8 in Human Saliva by SPR“, Lab on a Chip , 5(10):1017-1023, 2005.

Yi Liu et al., Linear Artificial Molecular Muscles, Journal of American Chemical Society, Vol. 127, pp. 9745-9759, 2005.

Li, Y., Denny, P., Ho, C.M., Montemagno, C., Shi, W., Qi, F., Wu, B., Wolinsky, L., and Wong, D.T., “The Oral Fluid MEMS/NEMS Chip (OFMNC): Diagnostic & Translational Applications”, Adv Dent Res , 18:3-5, June 2005.

Qiao Lin, Yong Xu, Fukang Jiang, Yu-Chong Tai, and Chih-Ming Ho, A Parametrized Three-Dimensional Model for MEMS Thermal Shear-Stress Sensors, Journal of Microelectromechanical Systems, Vol. 14, No. 3, pp. 625-633, June 2005

Wang T. H., Y. Peng, C. Chen, P. K. Wong, C. M. Ho “Single-Molecule Tracing on a Fluidic Microchip for Quantitative Detection of Low-Abundance Nucleic Acids“, Journal of the American Chemical Society (JACS) 127. 15 (2005):5354-5359.

2004

Journal Publications top

Deval, J., Umali T. A., Lan, E. H., Dunn, B., and Ho, C. –M., “Reconfigurable Hydrophobic/Hydrophilic Surfaces in Microelectromechanical Systems (MEMS)”, Journal of Micromechanics and Microengineering, Vol. 14, pp. 91 – 95, 2004.

Suzuki, H., Ho, C.M. and Kasagi, N., “A Chaotic Mixer for Magnetic Bead-Based Micro Cell Sorter”, Journal of Microelectromechanical Systems , Vol. 13, No. 5, pp. 779-799, 2004

Pak Kin Wong, Che-Yang Chen, Tza-Huei Wang, and Chih-Ming Ho , “Electrokinetic Bioprocessor for Concentrating Cells and Molecules Analytical Chemistry“, Web Release Date: 22-Oct-2004.

Pak Kin Wong, Jeff Tza-Huei Wang, Joanne H. Deval, Chih-Ming Ho, “Electrokinetics in Micro Devices for Biotechnology Applications”, IEEE/ASME Transactions on Mechatronics, vol 9, 366-376, 2004.

Lin, Q., Jiang, F., Wang, X., Xu, Y., Han, Z., Tai, Y.C., Lew, J. and Ho, C.M., “Experiments and Simulations of MEMS Thermal Sensors for Wall Shear Stress Measurements in Aerodynamic Control Applications”, J. of Micromechanics and Microengineering, 14(12):1640-1649, December 2004.

Wong, P.K., Ulmanella, U. and Ho, C.M., “Fabrication of Microsurgical Tools for Single-Cell and Intracytoplasmic Injection”, Journal of Microelectromechanical System, Vol. 13, No. 6, 940-946, 2004.

Maie A. R. St. John; Yang Li; Xiaofeng Zhou; Paul Denny; Chih-Ming Ho; Carlo Montemagno; Wenyuan Shi; Fengxia Qi; Benjamin Wu; Uttam Sinha; Richard Jordan; Lawrence Wolinsky; No-Hee Park; Honghu Liu; Elliot Abemayor; David T. W. Wong, “Interleukin 6 and Interleukin 8 as Potential Biomarkers for Oral Cavity and Oropharyngeal Squamous Cell Carcinoma“, Arch Otolaryngol Head Neck Surg, Aug 2004; Vol. 130 pp.929 – 935.

Tony Jun Huang, Hsian-Rong Tseng, Lin Sha, Weixing Lu, Branden Brough, Amar H. Flood, Bi-Dan Yu, Paul C. Celestre, Jane P. Chang, J. Fraser Stoddart, and Chih-Ming Ho, “Mechanical Shuttling of Linear Motor-Molecules in Condensed Phases on Solid Substrates“, Nano Letters, November 2004; Vol. 4, No. 11: pp 2065 – 2071

Huang, A.; Lew, J.; Xu, Y.; Tai, Y.-C.; Ho, C.-M., Microsensors and Actuators for Macrofluidic Control, Sensors Journal, IEEE , Volume: 4 , Issue: 4 , pp. 494-502, Aug. 2004

Hsiai T, Cho, S.K., Wong, P, Ing M., Salazar, A., Navab, M., Demer, L., Ho, C. M., “Micro Sensors: Linking Real-Time Oscillatory Shear Stress with Vascular Inflammatory Responses”, Ann Biomed Eng., Vol. 32, Issue 2, pp. 189-201, 2004.

Tony Jun Huang, Branden Brough, Chih-Ming Ho, Yi Liu, Amar H. Flood, Paul A. Bonvallet, Hsian-Rong Tseng, J. Fraser Stoddart, Marko Baller, and Sergei Magonov, “A nanomechanical device based on linear molecular motors“, Applied Physics Letters, November 29, 2004, Volume 85, Issue 22, pp. 5391-5393

Mingming Wu, Thomas Cubaud, and Chih-Ming Ho, “Scaling law in liquid drop coalescence driven by surface tension”, Physics of Fluids, July 2004, Volume 16, Issue 7, pp. L51-L54

T. Cubaud, C-M.Ho “Transport of bubbles in square microchannels”, Physics of Fluids (2004) Vol. 16, No 12, pp. 4575-4585