Dr. Peter Lillehoj

Vitatop

I was born in Rockville, MD and attended McDonogh School in Owings Mills, MD for my high school studies. Afterwards, I studied at Johns Hopkins University in Baltimore, MD, where I earned a B.S. degree in Mechanical Engineering. During this time, I developed an interest in micro-/nanotechnology and worked as an undergraduate researcher under the supervision of Professor Kevin J. Hemker. Later on, my research shifted towards the fields of microfluidics and biosensing and I worked in the laboratory of Professor Jeff T.H. Wang. For my graduate studies, I attended the University of California, Los Angeles under the guidance of Professor Chih-Ming Ho where my research focused on the development of microfluidic systems for bioprocessing and biodetection. Currently, I am a postdoctoral researcher at UCLA developing a novel cell phone based biosensor for rapid malaria detection (Grand Challenges in Global Health Award from the Bill and Melinda Gates Foundation), which I’m serving as the PI and project leader.

Research Intereststop

My research interests include BioMEMS, microfluidics, biosensors, lab-on-chips (LOCs) and point-of-care diagnostics. Specifically, my work focuses on the design, fabrication and integration of biomedical devices for current and emerging applications including clinical diagnosis, bio/homeland security and water/food safety. For my future research, I aim to develop microfluidic devices based on mobile platforms and point-of-care biomedical devices that are low cost, readily distributable and user friendly. Some of my other research interests include the development of simple and low-cost techniques for sample preparation & bioprocessing and innovative technologies to manufacture disposable, single-use biosensors for advanced health care diagnostics.

Educationtop

Ph.D., Mechanical Engineering, 2011
     Major Field: Micro-electrical-mechanical systems (MEMS) & Nanotechnology
     Minor Field: Biomedical Instrumentation
University of California, Los Angeles, Henry Samueli School of Engineering and Applied Science

M.S., Mechanical Engineering, 2007
University of California, Los Angeles, Henry Samueli School of Engineering and Applied Science

B.S., Mechanical Engineering, 2006
Johns Hopkins University, Whiting School of Engineering

Work Experiencetop

Postodoctoral Researcher (June 2011 – Current)
Molecular Mechanics Laboratory, University of California, Los Angeles

Graduate Student Researcher (September 2006 – June 2011)
Molecular Mechanics Laboratory, University of California, Los Angeles

Undergraduate Research Assistant (December 2005 – May 2006)
BioMEMS and Single Molecule Dynamics Laboratory, Johns Hopkins University

Undergraduate Research Assistant (May 2003 – December 2005)
Advanced Metallic and Ceramic Systems Laboratory, Johns Hopkins University

Patents and Publicationstop

Patents:
1. “ A cell phone SIM card-based biosensor” U.S. Provisional Patent 61/490,330.

2. “A self-pumping Lab-on-a-chip for rapid detection of botulinum toxin” U.S. Provisional Patent 61/295,571.

3. “Simple and robust hydrophilic coatings on poly(dimethylsiloxane)” UCLA invention disclosure.

4. “Hydrophobic Surfaces For Particle Concentration From Liquid Droplets” UCLA invention disclosure.

Peer-Reviewed Journal Articles:

1. P. B. Lillehoj, J. He, C. Kaplan, W. Shi and C.M. Ho, “A microfluidic platform for rapid detection of bacterial pathogens”, in preparation.

2. C. Wu, P. B. Lillehoj, L. Sabet, P. Wang, and C.M. Ho, “Ultrasonication on a microfluidic chip to lyse single and multiple Pseudo-nitzschia for marine biotoxin analysis”, Biotechnology Journal, 6, 150-155, 2011.

3. F. Wei, P. B. Lillehoj and C.M. Ho, “DNA Diagnostics: Nanotechnology-enhanced Electrochemical Detection of Nucleic Acids”, Pediatric Research, 67, 458-468, 2010.

4. P. B. Lillehoj, H. Tsutsui, B. Valamehr, H. Wu and C.M. Ho, “Continuous sorting of heterogeneous-sized embryoid bodies”, Lab on a Chip, 10, 1678 – 1682, 2010.

5. P.B. Lillehoj, F. Wei and C.M. Ho, “A self-pumping lab-on-a-chip for rapid detection of botulinum toxin”, Lab on a Chip, 10, 2265-2270, 2010.

6. Lina Li, Mary Beth Finnegan, Semiha Özkan, Young Kim, P. B. Lillehoj, Chih-Ming Ho, Renate Lux, Ron Mito, Zvi Loewy, and Wenyuan Shi, “In Vitro Study of Biofilm Formation and Effectiveness of Antimicrobial Treatment on Various Dental Material Surfaces”, Molecular Oral Microbiology, 25, 384-390, 2010.

Peer-Reviewed Conference Proceedings:

1. P. B. Lillehoj and C.M. Ho, A Long-term, Stable Hydrophilic Poly(dimethylsiloxane) Coating for Capillary-based Pumping, Proc. of 23rd IEEE MEMS 2010, 1063 – 1066 (2010)

2. C. Wu, P. B. Lillehoj, P. Wang, and C.M. Ho, “A Microfluidic Device for Single and Small Population Cell Trapping and Lysis of Pseudo-nitzschia”, Proc. of 5th IEEE NEMS 2010.

3. P. Lillehoj, N. Li, H. Tsutsui and C.M. Ho, “A Compact Microfluidic Continuous Flow Separator for Particle and Cell Sorting”, Proc. of 21st IEEE MEMS 2008, 292-295 (2008)

International Conference Presentations:

1. L. Li, M. B. Finnegan, S. Özkan, Y. Kim, P.B. Lillehoj, C.-M. Ho, R. Lux, R. Mito, Z. Loewy, and W. Shi, “Analysis of microbial biofilms on different dental material surfaces”, Poster presentation for the American Association for Dental Research (AADR), Washington, D.C., USA (2010)

2. P. Lillehoj and C.M. Ho, “A Long-term, Stable Hydrophilic Poly(dimethylsiloxane) Coating for Capillary-based Pumping”, Poster presentation for the 23rd Annual IEEE International Conference on Micro-Electro-Mechanical Systems (MEMS’10), Hong Kong, HK (2010)

3. C. Wu, P. B. Lillehoj, P. Wang, and C.M. Ho, “A Microfluidic Device for Single and Small Population Cell Trapping and Lysis of Pseudo-nitzschia”, Oral Presentation for the 5th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS’10), Xiamen, China (2010)

4. P. Lillehoj, N. Li, H. Tsutsui, and C.M. Ho, “A Compact Microfluidic Continuous Flow Separator for Particle and Cell Sorting”, Poster presentation for the 21st Annual IEEE International Conference on Micro-Electro-Mechanical Systems (MEMS’08), Tucson, AZ (2008)

5. H.C. Yeh, C.M. Puleo, T.C. Lim, P.B. Lillehoj, Y.P. Ho, K. Liu, and T.H. Wang, “Evaluation of Doxorubicin as Inhibitor of Sp1-DNA Complex by Fluorescence Correlation Spectroscopy on a Microfluidic Chip”, The Biomedical Engineering Society Annual Meeting (BMES2006), Chicago, IL, Oct. 11-14 (2006)

6. C.M. Puleo, H.C. Yeh, Y.P. Ho, P. Lillehoj, I.M. Shih, and T.H. Wang, “Assessment of Allelic Imbalance Using Microfluidic Enabled Single Molecule PCR”, The Biomedical Engineering Society Annual Meeting (BMES2006), Chicago, IL, Oct. 11-14 (2006)

Workshop Presentations:

1. P. Lillehoj, N. Li, H. Tsutsui, and C.M. Ho, “A Compact Microfluidic Continuous Flow Separator for Particle and Cell Sorting”, Poster presentation for the UCLA Engineering Technology Forum, Los Angeles, CA (2007)

2. R. Thompson, P. Lillehoj, C. Cionea, and K. Hemker, “Determining the mechanical properties of bond coats with microsample testing”, Poster presentation for the ONR/NSF Workshop on Thermal Barrier Coatings, Santa Barbara, CA (2005)

3. P. Lillehoj, K. Hemker, “Development of Strain Measurement Techniques in Microsample Testing”, Poster presentation for the Provost’s Undergraduate Research Awards, Baltimore, MD (2004)

Awards and Honorstop

• Recipient of a Grand Challenges in Global Healthcare grant from the Gates Foundation (2011)
• UCLA Dentist-Scientist and Oral-Health-Scientist Training Fellow (2009-2011)
• Xerox Technical Minority Scholarship (2009, 2010)
• UCLA Graduate Research Mentorship Fellowship (2008-2009)
• 1st Place, Johns Hopkins Mechanical Engineering Senior Design Project (2006)
• Vredenburg Scholarship (2005)
• Provost’s Undergraduate Research Award (2004)
• 2nd Place, Johns Hopkins Mechanical Engineering Design Competition (2002)
• Papa John’s Scholarship (2002)
• Maryland Distinguished Scholar (2001)

Contact Infotop

Mailing Address:
15-155 Engineering IV
420 Westwood Plaza
Los Angeles, CA 90095

Phone: (310) 825-9540
Fax: (310) 825-1350
Email: plillehoj at ucla.edu